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Neuraminidase inhibitors NAI are the most frequently used
2018-10-23
Neuraminidase inhibitors (NAI) are the most frequently used antiviral drug for management of influenza infection. Early NAI treatment was associated with shorter illness duration, and is most beneficial when treatment started within 2days of illness onset (Lee et al., 2015). However, except for indu
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flavopiridol For HCC the second leading cause of cancer deat
2018-10-23
For HCC, the second leading cause of cancer death worldwide, there is a lack of effective drugs. The only approved drug, sorafenib, has modest survival benefits (Llovet et al., 2008; Abou-Alfa et al., 2006; Cheng et al., 2009). Immunotherapy has been considered as an effective approach for cancer tr
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br Analysis of binding interface Direct atom
2018-10-23
2. Analysis of binding interface Direct acetylcholine receptors to atom contacts between BCMA and the VH and VL of J22.9-xi were identified using the PISA interaction server [9]. Direct and indirect hydrogen bonding interactions involving water were identified and validated (distance and geometr
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In the simulations the canards span
2018-10-22
In the simulations, the canards span freely until 5 s after launch. Fig. 9 shows the inherent vibration frequencies (include the fast and slow part) of 155 mm projectile during the entire flight domain. It can be seen from Fig. 5 when the rotation speed of the forward part is 0.5 revolutions per se
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Si la transgresi n es un gesto que
2018-10-22
Si la transgresión es un gesto que concierne al límite, nuestros informantes ejecutan dicho gesto, pero retroceden al mismo tiempo. Salomón, tal vez el informante más disruptivo de los entrevistados, pide que los leathers sean vistos como hombres normales que exploran aspectos nuevos o distintos de
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Aunque sea comprobable nuestra interdependencia corporal
2018-10-22
Aunque sea comprobable nuestra interdependencia corporal, es un hecho también que existen modelos piramidales de jerarquización corporal que producen lazos caracterizados por la explotación y el disciplinamiento. Este es el caso de quien cuida de la persona con síndrome de Down, donde las nociones d
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One interesting finding of this
2018-10-22
One interesting finding of this study that is noteworthy has to do with the observation indicating that despite the fact that most of the buildings sampled have external doors made up of steel and burglary proof windows, the respondents appear to be dissatisfied with the general security situation i
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In the frame of the
2018-10-22
In the frame of the researches on dendriform structures, some researchers have attempted to explore the efficiency of tree׳s fractal-like branching structures with completely different angles. In a research-oriented ‘Fibrous Structures’ workshop hosted by the Istanbul Technical University in Istanbu
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To evaluate the visual comfort in
2018-10-22
To evaluate the visual comfort in this tie2 case, the Daylight Glare Probability (DGP) (Wienold and Christoffersen, 2006) was used as an indicator, which can be expressed as follows:where E is the total vertical eye illuminance [lx], is the solid angle of the glare source [sr], L is the glare sour
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When application of simple public address system
2018-10-22
When application of simple public address system based on the electro acoustics installed at the cathedral, improved sound pressure and clarity (SPL, C80, D50, ITDG, and RASTI were improved significantly, excluding reverberation characteristics) can be acquired as follows: SPL (74.5 dBA on average),
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br Results br Discussion Lumbar
2018-10-22
Results Discussion Lumbar hernia is a rare posterior abdominal wall defect that accounts for less than 1.5% of the total hernia events. Only 200–300 cases have been reported in the literature. The lumbar area is a confined space bordered by the lower edge of the 12th rib superiorly, the iliac
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p-gp inhibitors list In some series high ligation of
2018-10-22
In some series, high ligation of the hernia sac was proposed as a time-consuming procedure and was associated with higher postoperative pain intensity. In our series, there was no significant difference in pain intensity, and the rate of postoperative complications was the same between the ligation
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In total patients men and women with a median age
2018-10-22
In total, 215 patients (124 men and 91 women), with a median age at operation of 53 years (range, 16–89 years) were included. Pathological staging according to the seventh edition of the AJCC Manual showed Stages 0, I, and II for three patients, 142 patients, and 70 patients, respectively. Overall,
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mps1 kinase br Case Report The patient was an year old
2018-10-22
Case Report The patient was an 83-year-old Asian man (68.7 kg, 165 cm; body mass index: 25.2 kg/m2) with multiple comorbidities including diabetes mellitus, chronic heart failure, and a left inguinal hernia. He had undergone Bassini hernioplasty 10 years previously. He had sustained a left intert
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Previous research employing mammalian and
2018-10-22
Previous research employing mammalian and chick primary CGP 41251 has demonstrated that spinal motoneurons are extremely sensitive to BoNT/A when compared to poorly sensitive DRGs. Our analysis is consistent with those findings, indicating that ES cell-derived motoneurons, which are equivalent to p
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