• Introduction Brugada syndrome is severe arrhythmia character

  2019-06-28

  

  Introduction Brugada syndrome is severe arrhythmia characterized by specific ST elevations in precordial leads and sudden ventricular fibrillation (VF), and the condition may result in sudden cardiac death [1–5]. By implanting defibrillation devices, also known as implantable cardioverter-defibrill

• In the present study we found that stathmin

  2019-06-28

  

  In the present study, we found that stathmin was significantly down-regulated upon treatment with a combination of Zol and gefitinib. The down-regulation of stathmin, which was not detected by 2-D DIGE after treatment with either agent alone, was considered to be attributable to cooperative effect o

• br Materials and methods A retrospective questionnaire surve

  2019-06-28

  

  Materials and methods A retrospective questionnaire survey was conducted among 299 JHRS institutions from December 2012 to January 2013. Patients with persistent AF who underwent TEE for elective ECV were included. LA thrombus incidence, risk factors for thrombus formation as indicated by the CHA

• br Results Compared to the respective

  2019-06-28

  

  Results Compared to the respective untreated groups, the VT duration was shorter in clonidine-treated ETB-deficient rats during phase I and in wild-type rats during phase II (Fig. 1A). Heart rate (HR) increased in both untreated groups, but this response was blunted after clonidine, mainly in ETB

• br We appreciate the response by Sharath

  2019-06-28

  

  We appreciate the response by Sharath Nagaraja and Ritesh Menezes to our Comment, in which we had argued that patients with tuberculosis deserve a complete and patient-centric solution, irrespective of whether they seek care in the public or private health sector. Nagaraja and Menezes seem to have

• Previous studies have demonstrated localization

  2019-06-27

  

  Previous studies have demonstrated localization of miR-21 staining in stromal tool of OSCC associated with the tongue and mouth floor—this might be a useful prognostic predictor. We also observed miR-21 staining in the stromal cells of tumors. However, since multiple lines of evidence indicate the i

• br Discussion In our patient series coronary

  2019-06-27

  

  Discussion In our patient series, coronary angiography was performed routinely prior to electrophysiological study, revealing a 9.1% (5/55) incidence of significant coronary artery stenosis in patients with Brugada syndrome/Brugada-type ECG. Although acute myocardial ischemia has been reported to

• Calyculin A structure br Introduction Despite the widespread

  2019-06-27

  

  Introduction Despite the widespread use of bone-targeted agents in the care of patients with bone metastases from prostate and breast cancer, questions regarding the optimal; choice of agent, dose, dosing frequency, and duration of therapy remain unanswered [1–6]. Our research group is interested

• Cathepsin G Inhibitor I br Acknowledgements br Introduction

  2019-06-27

  

  Acknowledgements Introduction The chronic myeloproliferative neoplasms (MPN) comprise a group of clonal stem cell disorders with a high prevalence of the JAK2 V617F mutation (JAK2+) causing excessive production of mature blood cells. Transformation to acute myeloid leukemia (AML) is seen in 2–

• The coverage and quality of laboratory services throughout A

  2019-06-27

  

  The coverage and quality of laboratory services throughout Africa is inadequately documented. Quality provided by individual laboratories is questioned, and not all facilities are enrolled in external quality assurance schemes. For example, in 2013, an evaluation of accredited laboratories in sub-Sa

• br Basis and methodology of DCE MRI DCE MRI

  2019-06-27

  

  Basis and methodology of DCE-MRI DCE-MRI images are performed by using injecting low-molecular-weight gadolinium chelated contrast agent with a constant, stable rate. The contrast agent is carried by blood flow into the tissue, causing increased signal intensity (SI) of the T1-weighted images due

• Thomas Hoeksema por su parte explica

  2019-06-27

  

  Thomas Hoeksema, por su parte, explica la paradoja del título del siguiente modo: “la destrucción (fuego) está moderada por la estabilidad y la armonía (reposo). La relación entre estas dos fuerzas es multidimensional y dialéctica”. Para Hoeksema, el segundo volumen poético de Pacheco se debe entend

• No es xito peque o que bajo la direcci

  2019-06-27

  

  No es éxito pequeño que “bajo la dirección del maestro Stols” (así indica el colofón del libro) se lograse tal parecido con ellas, pero conviene subrayar que Jusep Torres Campalans no es mera mímesis material de la colección Le goût de notre temps sino también, o ante todo, estructural. El Picasso d

• Paratyphi A could have a large

  2019-06-27

  

  Paratyphi A could have a large effect if Vi-polysaccharide-conjugate vaccines are introduced in Asia. The absence of the Vi-polysaccharide Chelerythrine Chloride molecular in Paratyphi A is the most important microbiological discrepancy between Paratyphi A and Typhi; vaccines based on Vi-polysa

• br Tara Mangal and colleagues document the struggle to elimi

  2019-06-27

  

  Tara Mangal and colleagues document the struggle to eliminate polio in northern Nigeria. However, they overlook the importance of routine immunisation to polio eradication efforts. The investigators identified an association between the risk of contracting polio and oral polio vaccine unavailabil

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