• In the current investigation we studied the effect of propof

  2024-08-15

  

  In the current investigation, we studied the effect of propofol on prostate cancer cells. Propofol is one of the most commonly used drugs in the critical care setting and for the induction of general anesthesia and moderate and deep sedation intraoperatively. Recent studies indicated that propofol e

• Cy5 carboxylic acid (non-sulfonated) Although our sample siz

  2024-08-15

  

  Although our sample size is not enough to conclude that there is no great genetic variation of the AR gene in most New World monkeys, it would be reasonable to state that the microsatellite region in the exon 1 of the androgen receptor gene of New World monkeys (platyrrhine) is relatively shorter th

• br Conclusions Extract of non germinated winter rape seeds c

  2024-08-15

  

  Conclusions Extract of non-germinated winter rape seeds cv. Bellevue was screened for the aminopeptidase activity. It revealed broad substrate specificity, with the highest activity toward Phe-pNA. Also in the partially purified sample, phenylalanine was preferentially hydrolysed. PMSF, known ser

• In the present study AP B

  2024-08-15

  

  In the present study, AP31-B preferentially released hydrophobic Deoxycholic acid such as leucine and alanine from N-terminal of peptide (Fig. 4). The debittering ability of AP31-B seemed to depend on such substrate specificity, but additional tests against other hydrophobic amino acids are needed

• br Adenosine receptors and the adaptive immunity T lymphocyt

  2024-08-14

  

  Adenosine receptors and the adaptive immunity T lymphocytes are responsible for the cell-mediated immune response [95]. These cells can be stimulated by the presentation of antigenic moieties by APCs, such as dendritic cells or macrophages [96]. The presentation of antigenic molecules on the APC

• Adenosine is an endogenous nucleoside that plays

  2024-08-14

  

  Adenosine is an endogenous nucleoside that plays pivotal roles in different physiological and pathophysiological processes by triggering specific cell-surface receptors both in the Sal 003 sale and in the periphery. The adenosine receptors (ARs) are four different subtypes of G protein-coupled rece

• Temafloxacin hydrochloride There are several reports about t

  2024-08-14

  

  There are several reports about the expression of AChRs and their modulation to osteogenic factors in osteoblasts (Rothem et al., 2011, Sato et al., 2010, Walker et al., 2001). The normal osteocytic MLO-Y4 Temafloxacin hydrochloride expressed multiple subtypes, which was demonstrated by the detecti

• During myeloid cell maturation expression of LO

  2024-08-14

  

  During myeloid cell maturation, expression of 5-LO mRNA and protein is strongly induced (60–130-fold) by calcitriol (1,25(OH)2D3) and transforming growth factor-β (TGFβ) [6,7]. The upregulation of 5-LO mRNA transcription is mainly due to transcript elongation and mRNA maturation [8,9]. Interestingly

• Based on the observation that antipsychotic drugs

  2024-08-14

  

  Based on the observation that antipsychotic drugs increase 5-HT1A–D2 heteromerization level (Łukasiewicz et al., 2016), we set out to compare the effect of paroxetine to that of risperidone. Paroxetine, a potent SSRI, is very effective in the treatment of depression and anxiety disorders, e.g., gene

• NOXA a member of the pro apoptotic B

  2024-08-14

  

  NOXA, a member of the pro-apoptotic B-cell lymphoma 2 (BCL-2) family, plays a vital role in regulating mitochondrial or inherent apoptotic pathways [7,8]. NOXA binds to MCL-1 with high affinity and interacts with A1 (known as BCL2A1), resulting in BIM release to trigger subsequent apoptosis [9]. In

• A contribution of V ATPase subunits specifically

  2024-08-14

  

  A contribution of V-ATPase subunits specifically to phagosome-lysosome fusion was uncovered by Peri and Nüsslein-Volhard who described that depletion of the VO subunit a1 in zebrafish interferes with phagosome maturation in microglial protase (Peri and Nusslein-Volhard, 2008). However, loss of the

• As shown in B the recombinant human

  2024-08-14

  

  As shown in B, the recombinant human 15-LOX-1 (30nM) showed a time-dependent increase in fluorescent signal, and signal development was almost completed within 20min in the presence of 50μM arachidonic ApoBrdU DNA Fragmentation Assay Kit and 5μM DHR. For both purified enzyme and cell lysates, the e

• br ACL A Metabolic Checkpoint for Sensing Excess Nutrients D

  2024-08-14

  

  ACL: A Metabolic Checkpoint for Sensing Excess Nutrients? During normal transitions between fasting and feeding, cells maintain energy homeostasis by integrating energy and nutrient status signals at key metabolic nodes, coordinating multiple processes. For example, the AMP-activated protein kina

• Introduction Lipoxygenases LOXs are key enzymes that

  2024-08-14

  

  Introduction Lipoxygenases (LOXs) are key enzymes that catalyze the polyunsaturated fatty acids (PUFAs) such as arachidic ascorbic acid (AA), linoleic acid (LA) and others unsaturated fatty acids (Brash, 1999). LOXs are expressed in immune, neural, epithelial, tumor cells and other cells (Claesson

• Telomerase action at the telomere is highly regulated it

  2024-08-14

  

  Telomerase action at the telomere is highly regulated; it preferentially elongates the shortest telomeres, and recruitment of the enzyme complex to the telomere occurs in mid-S phase of the cell cycle (Bianchi and Shore, 2007, Britt-Compton et al., 2009, Teixeira et al., 2004, Hemann et al., 2001, T

15641 records 51/1043 page Previous Next First page 上5页 5152535455 下5页 Last page