• Foreign polypeptide antigens can be incorporated into

  2022-07-26

  

  Foreign polypeptide antigens can be incorporated into VLPs to create “chimeric” structures, either as fusions to either end of the VLP capsid (coat) protein (CP) or as additions to well-presented loops [18]. This kind of direct fusion to the coat is usually good for small peptides, however, larger p

• Reports of hyperlocomotion after administration

  2022-07-26

  

  Reports of hyperlocomotion after administration of ALX-5407 [27] coupled with the lack of hyperlocomotion after administration of SSR504734, a non-sarcosine, long-residence time, competitive inhibitor [19], suggested that the GlyT1 inhibitor chemotype may impact OP. Furthermore, a compound with a co

• Neurotransmitter transporters are rapidly recycled

  2022-07-26

  

  Neurotransmitter transporters are rapidly recycled from and to the membrane. For instance, the GABA transporter GAT1 is recycled in a calcium and depolarization dependent manner. GAT1 located in the plasma membrane is internalized to a subpopulation of small vesicles different from the classical neu

• Capillary monolithic columns obtained by in situ polymerizat

  2022-07-26

  

  Capillary monolithic columns obtained by in situ polymerization have been developed rapidly as an efficient chromatographic stationary phase, which exhibits excellent reproducibility, reliable stability and fast transfer kinetics [18]. Recently, it has been extensively applied in capillary liquid ch

• Mast cells isolated from mice

  2022-07-26

  

  Mast crizotinib receptor isolated from mice and rats are able to take up histamine from the microenvironment (Day and Green, 1962, Cabut and Haegermark, 1966). It has been considered that the uptake of extracellular histamine into bone marrow-derived mast cell granules is mediated by two membrane tr

• Shikonin represents naphtoquinonic compound isolated from th

  2022-07-26

  

  Shikonin represents naphtoquinonic compound isolated from the Chinese plant Lithospermum erythrorhizon[20]. Shikonin treatment inhibits AKT and ERK signaling pathways and induces apoptosis through FOXO transcription factors and mitochondrial pathway [21], [22]. Recent results suggest inhibition of l

• Glucocorticoid is a major regulator of body s response

  2022-07-25

  

  Glucocorticoid is a major regulator of body's response to stress (Armario, 2006). Repeated injections of the glucocorticoid corticosterone (CORT) in mice have been shown to produce an animal model of depression (Zhao et al., 2008). Further study of this phenomenon suggested that prolonged CORT expos

• br Acknowledgments The authors gratefully

  2022-07-25

  

  Acknowledgments The authors gratefully acknowledge the support provide by National Natural Science Foundation of China (Number 31301415). Introduction β-Galactosidases (EC 3.2.1.23), frequently known as lactases, are widely used in lactose hydrolysis. This disaccharide is present in mammalian

• In conclusion our results show that

  2022-07-25

  

  In conclusion, our results show that multiple receptor populations can be expressed when α4, β3 and δ mRNAs are injected into Xenopus oocytes and include β3 homomeric; α4β3; and β3δ receptors. The previously unidentified β3δ can be differentiated pharmacologically from either β3, α4β3 and α4β3δ rece

• br Results br Discussion The inflammasome consists

  2022-07-25

  

  Results Discussion The inflammasome consists of the sensor molecule nucleotide oligomerization domain (NOD)-like receptors (NLRs), the adaptor protein ASC, and the ceritinib mg molecule CASP1 (Guo et al., 2015). Among the different types of inflammasome, the NLRP3 inflammasome requires a primi

• Fig summarizes the results for M

  2022-07-22

  

  Fig. 1 summarizes the results for 500 μM concentration of the drugs. Action of histamine is presented for comparison. Both 1-methylhistamine and Nα-methylhistamine strongly potentiated ASIC1a responses. The concentration-dependence of action of Nα-methylhistamine was measured (Fig. 1B). Fitting by H

• Furthermore the identification of the inhibitory effect

  2022-07-22

  

  Furthermore, the identification of the inhibitory effect of P. grandiflorum and ginseng extract on HDAC represents an effective workflow for gene expression similarity-based repositioning of nutraceuticals. Acknowledgments This research was supported by Basic Science Research Program through the

• While published data around the functional significance of G

  2022-07-22

  

  While published data around the functional significance of GPR84 are quite sparse, details of signaling pathways initiated by the receptor are even more limited, including in recombinant systems. In recombinant cells, GPR84 activation reportedly leads to Gi pathway activation, resulting in pertussis

• Methods br Results br Discussion The current study

  2022-07-21

  

  Methods Results Discussion The current study is the first to specifically investigate the role of hepatic GPR109A and GPR109B on HDL metabolism and response to niacin therapy. While niacin raises HDL-C levels in humans, it has been reported by others [20], [36] and confirmed by us here that n

• New follicular wave emergence is associated closely with the

  2022-07-21

  

  New follicular wave emergence is associated closely with the stage of the estrous Outcome (Sirois and Fortune, 1988). As indicated by results from the present experiment, cows that had regression of the largest follicle on Day of treatment onset had follicle wave characteristics that were consistent

15695 records 378/1047 page Previous Next First page 上5页 376377378379380 下5页 Last page